Low body temperature increases lifespan

It was long theorised that low body temperature possibly will prolong life. On November 2006, a team of scientists from the Scripps Research Institute detailed that transgenic mice which had body temperature 0.3-0.5 C lower than usual mice (because of overexpressing the uncoupling protein 2 in hypocretin neurons (Hcrt-UCP2), which important hypothalamic temperature, thus forcing the hypothalamus to lower body temperature) definitely lived longer than normal mice. The lifetime was 12% longer for males and 20% longer for females. Mice were permissible to eat as much as they wanted. The effects of body temperature on prolonged existence have not been studied in humans.